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Celexa and placebo groups were compared with respect to1mean change from baseline in vital signspulsesystolic blood pressureand diastolic blood pressureand2the incidence of patients meeting criteria for potentially clinically significant changes from baseline in these variablesThese analyses did not reveal any clinically important changes in vital signs associated with Celexa treatmentIn additiona comparison of supine and standing vital sign measures for Celexa and placebo treatments indicated that Celexa treatment is not associated with orthostatic changes.

Musculoskeletal System DisordersInfrequentarthritismuscle weaknessskeletal painRarebursitisosteoporosis.

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